O and P or M Directing (lower quality)

Have fun studying Organic Chemistry as you sing along with this science spoof of "Route 66." Memorize the deactivating and activating substituents for aromatic rings.

If you have an aromatic ring
Is the substituent activating?
O- and p- or m- directing?

First meet the deactivating eight
They think meta-positioning is great
Least to most, rank the reactive trait:

First, tertiary amine
That's --NR3
Nitro and Nitrile
Sulfone and Ketone
Now don't forget
Carboxylic acid
Then comes queen ester
Aldehyde's past her
Meta-directing
Deactivating

Halogens are crazy, mixed-up guys
They ortho, para- direct before your eyes
But weak deactivators, that's the big surprise

First in the line
Here's Iodine
Bromine, Chlorine, Reactive Fluorine (*notice after Iodine, they're alphabetized)
Here we are
Neutral with Hydrogen
Six more to rehearse
Look in the next verse
Even more reactive, of course

Phenyl and alkyl activate
Keeping rings in a more reactive state
Ortho, para direction is innate

Then amide and ether,
Hydroxyl and amine
Amine's most reactive
Of the whole thing
Donating
Electrons to the ring.
That's activating,
Always directing
Ortho, para,
Disubstituting

If you have an aromatic ring
Is the substituent activating?
O- and p- or m- directing?

O- and p- or m- directing?

Category:

Music

Tags:

• Organic
• Chemistry
• spoof
• route
• 66
• aromatic
• ring
• science

[17random8917]

Never thought anyone could combine organic chemistry and jazz. Very nice!

[cycro27]

LOL

[Cariced]

LOL =)