Provigil: An oral drug first approved by the FDA in 1998 for the treatment of narcolepsy, a condition in which there is an uncontrollable desire to sleep. Provigil promotes wakefulness. In 2004 the FDA also approved Provigil for the treatment of obstructive sleep apnea and sleeping problems caused by shift work. Provigil is said to be in common "off-label" use by college students, truckers, and others who want to stay awake when normally they should be sleeping. The drug is reportedly also being prescribed for numerous other problems including fatigue, depression, multiple sclerosis, and ADHD (attention deficit hyperactivity disorder). Some of these "off-label" uses may prove legitimate while others may be abuses of the drug. Provigil stimulates the brain without producing the jitteriness of caffeine or the addiction and euphoria of amphetamines. Provigil is believed to act by affecting dopamine and other neurotransmitters including histamine and norepinephrine. It is sold under the brand name Provigil. HOW TO USE Provigil: Take by mouth, in the morning, as directed. Use this medication exactly as prescribed. Do not increase your dose, take it more frequently or use it for a longer period of time than prescribed because this drug can be habit-forming. Also, do not stop using this drug without your doctor's approval. The recommended dose of PROVIGIL is 200 mg given once a day. For patients with narcolepsy and OSAHS, PROVIGIL should be taken as a single dose in the morning. For patients with SWSD, PROVIGIL should be taken approximately 1 hour prior to the start of their work shift. Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg dose SIDE EFFECTS: Nausea, diarrhea or headache may occur. If these effects persist or worsen, notify your doctor promptly. Report promptly: trouble sleeping, dizziness, mental/mood changes, loss of appetite, dry mouth. Unlikely but report promptly chest pain, fast/irregular pulse, vision changes, increased thirst/urination, trouble with urination, trouble with ejaculation, unusual muscle weakness or stiffness, muscle tingling or twitching. In the unlikely event you have an allergic reaction to this medication, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist. PRECAUTIONS: Tell your doctor your medical history, including: mental/mood problems, high blood pressure, heart problems, liver problems, kidney problems, allergies (especially drug allergies). Avoid alcohol intake, as it may intensify certain side effects of this drug. Caution is advised when performing tasks requiring alertness (e.g., driving). Caution is advised when this drug is used in the elderly, as they may be more prone to drug side effects. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. Consult your doctor before breast-feeding. DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially of: MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, phenelzine, procarbazine, selegiline), seizure medications (e.g., phenytoin, phenobarbital, carbamazepine), tricyclic antidepressants (e.g., amitriptyline, clomipramine), "blood thinners" (e.g., warfarin), azole antifungals (e.g., ketoconazole, itraconazole), rifamycins (e.g., rifampin, rifabutin), cyclosporine, diazepam, theophylline, propranolol. This medication may interfere with the effectiveness of hormone-type birth control. Discuss using other methods of birth control with your doctor. Do not start or stop any medicine without doctor or pharmacist approval. OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose include fast heartbeat, trouble sleeping, agitation, and restlessness.
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Drugs that make you smarter, and my experiences with them.by joejban9,464 views
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