BioE 243 Project May 2009 Protein Folding HP Cubic Lattice

The most impressive video on the web that demonstrates protein folding is from the Dill Lab at UCSF (http://www.dillgroup.ucsf.edu/dl_images/funnel/ProteinG_Fold_With_Landscape.mov­). This video is more modest; it uses HPview (Martin Mann, Sebastian Will, and Rolf Backofen (2008) CPSP-tools - Exact and Complete Algorithms for High-throughput 3D Lattice Protein Studies. BMC Bioinformatics. 9:230.) to spin the HP configuration about the vertical while the action is being captured by Techsmiths Snagit program (www.techsmith.com). Each captured clip is of a single configuration with a known energy continuing to be minimized. HPview displays the HP backbone model using green for the H monomers and gray for the P monomers. Several of these clips are created for lower and lower energies (V=-8 to V=-77). These clips are then assembled in Adobe's Premiere program (www.adobe.com).

Category:

Education

Tags:

• Protein
• Folding
• HP
• Cubic
• Lattice

[cmvb]

Very nice! Are you working on a bioinformatic's project?