Magnetic Separation of Gold Nanoparticles
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Uploaded by MANash101 on Mar 20, 2010
The video shows a cuvette (4mm in width) containing a mixture of gold and iron oxide nanoparticles with smart polymer coronas that are magnetically separated over the course of 20 minutes. See http://pubs.acs.org/doi/abs/10.1021/bc100180q
Also see: http://www.biophysik.physik.uni-muenchen.de/personen/postdoc/michael_nash/ind...
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@UniSonBBS The gold is block with a polymer called poly(N-isopropylacryalmide) which switches from hydrophilic to hydrophobic in response to salt or temperature above ~35 C. When the polymer switches it causes the magnetic and gold particles to cross-link (through hydrophobic interactions) enabling magnetic separation of the gold.
MANash101 6 months ago
Was the gold blocked before you added the NaCL? My gold particles crash if I dont.
UniSonBBS 7 months ago
@mmaaxx1198 Thanks for your comment. Gold is not magnetic but we used a mixture of gold an iron oxide nanoparticles that are cross aggregated through a "smart" polymer corona made of poly(N-isopropylacrylamide) polymers. This causes the iron oxide and gold particles to clump together allowing for magnetic forces to be applied to the gold nanoparticles.
MANash101 1 year ago
How is this possible? Gold isn't magnetic.
mmaaxx1198 1 year ago