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Skin Cancer Melanoma Biopsy and Histology

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Uploaded by on May 2, 2010

Dr. James L. Campbell Jr., MD discusses Skin Cancer Melanoma Biopsy and Histology. See more at http://www.dermnet.com PLEASE RATE AND COMMENT!!!
Biopsy and histology




Biopsy all suspicious lesions. Palpate the regional nodes prior to biopsy and document the findings. The only ""perfect"" biopsy technique is complete excision of the

entire lesion into subcutaneous fat. This allows for accurate measurement of the thickness of the lesion in millimeters referred to as the Breslow depth of invasion.




Biopsy and histologic

review distinguish melanoma from other tumors. All nevi which are removed for diagnostic or cosmetic purposes should be submitted for histologic review. Incomplete excision or biopsy of nevi can

lead to recurrence with epidermal hyperplasia of atypical appearing melanocytes. This recurrent nevus phenomenon can be clinically and histologically indistinguishable from superficial spreading

melanoma. The original excision or biopsy must be available for review to exclude a diagnosis of melanoma.

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