INTRA CYTOPLASMIC SPERM INJECTION (ICSI)
Until the 90's males with very low counts (less than 5 million per ml) or poor quality sperms had no hope of fathering children. This problem was surmounted by the new breakthrough of ICSI, which took place in Brussels, Belgium in 1992.
Since then, many such patients have fathered a child. We started our own ICSI programme in 1995-96 and have performed till date more than 800 cycles with success rate of 30 to 40%, which is comparable to the best units in the world.
In ICSI all the steps are similar to the procedure of IVF, except the step of fertilization. Normally in IVF one egg is mixed with 100,000 sperms and one of the sperms fertilizes the egg on its own. In contrast, in ICSI each egg is held and injected with a single live sperm. This micro-fertilization is done with the help of a machine called the Micromanipulator.
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