MFDEP cell loading device proof-of-concept

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Uploaded by on Jan 14, 2008

Proof-of-concept of a MEMS device that I designed for my PhD dissertation, at the University of Maryland. Cells are loaded inside a micro-cell cage using dielectrophoresis. The active cancellation of the parasitic traps is necesary, thus becoming the use of multiple frequencies (MFDEP). This is the first machine of its kind, and it is very useful if you need to load 1000's of cells inside cages in matter of seconds. This technology is part of the "Cell Clinics" project (PI: Elisabeth Smela). The cells used are yeast cells. See the article entitled "Parasitic Trap Cancellation Using Multiple Frequency Dielectrophoresis, Demonstrated by Loading Cells into Cages", upcomming in the journal Lab on a Chip.

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