Pediatric Acute Myeloid Leukemia (AML)

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Uploaded by on Feb 18, 2011

Jennifer McNeer, MD, a pediatric hematologist at Comer Children's Hospital at the University of Chicago, shares how advanced diagnostic techniques help physicians to better characterize and treat each child's case of acute myeloid leukemia (AML). Learn more about the symptoms, diagnosis, and treatment options for childhood acute myeloid leukemia.

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  • @berrin1223 *pray*

  • Please for my brother he has AML

  • Acute myeloid leukaemia (AML) is a cancer of blood-forming cells in the bone marrow. Abnormal immature white blood cells (blasts) fill the bone marrow and spill into the bloodstream. Production of normal blood cells is affected, causing anaemia, bleeding problems and infections. Treatment is mainly with chemotherapy. The outlook varies and depends on factors such as the exact sub-type of the AML and your age.

  • Inadequate post-transfusion platelet count increments can be due to a number of host-related factors such as: splenomegaly, severe infection with high fever, disseminated intravascular coagulation, drug-mediated antibodies and/or alloimmunization, and occasionally by administration of platelets damaged or activated during collection or storage. Lymphocytotoxic antibody directed against HLA-A or -B antigens is an excellent serologic marker for alloimmunization.

  • Refractoriness to infused platelets becomes a major clinical problem for many patients with acute myeloid leukemia (AML).

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