Ribosome or Ribozyme?

Chip Hunter and Tufan Gokirmak present the evidence that the ribosome is functioning as a catalytic unit in protein synthesis. The structure and catalytic properties of the rRNA are discussed, with emphasis on novel reagents and base-pair interactions. This presentation is the YouTube component of a graduate journal colloquium in Transformative Advances in Molecular Biology at the University of Florida. The course is part of the Horticultural Sciences Department and the Graduate Program in Plant Molecular and Cellular Biology and was led by Dr. Mark Settles and Dr. Kevin Folta.

Category:

Science & Technology

Tags:

• Ribosome
• ribozyme
• rRNA
• translation
• PMCB
• University of Florida
• Settles
• Folta

[PlantMolCellBio]

Not necessarily.  The original work called it cosuppression because it was consistent with other reports at the time of gene silencing upon overexpression. RNAi is one way that this is achieved, but there also are hard changes in DNA (like methylation) that occur as well to silence the process at the level of transcription. At the time of Napoli et al it was unknown what the mechanism actually was, but it was clear that something revolutionary was happening!

[DeMoNiOMx]

nice i am working now with 5S rRNA from Trypamosomatids :D cheers from Mexico

[raydern]

Rnai and co-suppression is a same process?