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Slings and anchors

The American Society for Cell Biology ASCB The American Society for Cell Biology ASCB·75 videos
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Published on Dec 17, 2012

To approach an infection site, rolling neutrophils use tethered slings to anchor themselves as they navigate high-shear blood flow that threatens to sweep them away
The video looks like something out of an action-adventure movie instead of a cell biology experiment. The action hero is a neutrophil, a type of white blood cell or leukocyte and a critical player in the immune system that defends us against bacteria and other pathogens. To attack a bacterial infection in tissue, neutrophils have to leave the blood stream and approach the infection site through tiny venules that are part of the microcirculation system.

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