Aubrey de Grey - WIRED Article - Audio version

Thursday, June 26th, 2008

Wired published an article detailing Aubrey de Grey's progress in his ongoing crusade to defeat aging as a disease. The article came out a day before Aubrey kicks off the first Methuselah Foundation sponsored conference on aging in the United States.

For the WIRED article visit:
http://www.wired.com/medtech/health/news/2008/06/methuselah?currentPage=all

Aging 2008: The Disease - The Cure - The Implications.

REGISTER HERE:
http://www.mfoundation.org/Aging2008/tickets/

Category:

Science & Technology

Tags:

• aubrey
• de
• grey
• methuselah
• foundation
• sens
• ending
• aging
• 2008
• UCLA
• m-prize
• life
• extension
• wired

[stancruse]

I need to interject... The human brain is far more capable than you believe. If you really listen, you will hear and understand every word. The problem is that many people are too distracted to calm their busy minds and really listen to anyone or anything. I purposefully slowed down and edited this text to speech for you to be able to understand it. If you still can't understand, there is a link to the article in the sidebar and you can read it. I listen at twice this speed.

[Tnias13]

Yeah, that's too annoying to hear all the way through....put a real voice please

[stancruse]

I'll see what I can do. It's a good article though. There's a link in the sidebar to it if you're interested in reading the text.

[curingaging00]

aubrey de grey is one of my favorite famous people.

my greatest wish is that aging will one day be cured before I die. and people like him are going to it happen!

he convinced me that aging is curable and will be stopped. and the first 1000 year old person is probly alive today.

[oddjobmj]

... You know this is a computer talking, right?

[RyanLoveheart]

I don't know why this guy thinks this guy is such a genius, i mean isn't it the goal of science to prolong human life and isn't this the inevitable end. I mean Robert Heinlen was writing about this decades ago. Also the fact that this idea has so many detractors is ridiculous when you consider the amount of money and effort goes into medical science. I'd like to see all the detractors refuse health-care when actually faced with death, then we'd really know who's on what side.

[Kafka1479]

DeGrey was right when he said that in 7 or 8 years, scientists will be able to reverse aging in mice....except it took 3 years not 8.

[ermills]

I haven't a clue of how long it would take for scientists to rejuvenate all of the brain, but one could imagine that to do this it would take nano computers (perhaps) to achieve the level of precision that you would want --at least when figuring adding to our knowledge in proteinomics..the research in genomics alone would obviously be insufficient....This concludes my thoughts on the topic

[ermills]

Rejuvenating our minds in an exact way or even close should not be a problem within itself (even though there are many reasons against messing with the mind)...Still, if you're old and on your death bed due to a brain ailment then you may be for rejuvenation.

[ermills]

or with hybridization of one part of a genome to another may transform a cell back to a naive state, which can then be modified to serve in memory (induce dendritic changes) and so forth ).Secondly, we already 10 trillion cells per day (and have to replenish them) throughout the body. We change all of the time. We lose skin cells every day...

[ermills]

Also, factors 'could' be and to some extent have been added to neurons to cause changes such as dendritic spindle changes (changes which represent our memories).

To reprogram a cell you need another cell's cytosolic contents (with transcription factors). So the idea of rejuvenating the brain is not so far-fetched when I know with 100% certainty that they can already reprogram neural cells (especially in Parkinsons to make dopaminergic neurons by adding factors to precursor cells

[ermills]

First, you already have stem cells in the brain that may replace some types of damaged neurons, but there are limitations and these stem cells may not differentiate to all neuron types in the lab (e.g., hippocampal vs cortex neurons). is something to be excited about for next couple of decades.

[ermills]

I don't think it's impossible to cure the causes of aging. Someone pointed out that scientists can't do much about the brain (their example, 20 year old body with 100 year old brain).  This point is debateable for two reasons --with many run-on sentences and typos:

[IcarusFlying]

@mutantguitarist123 That's why we must continue to advance education, Independence, and clarity of mind. It is when people can not be swayed from the good path through insight, clarity, and good reason, that attempts to do otherwise will easily rebounded.

[IcarusFlying]

@stancruse There needs to be more resources out there to help people clarify, organize, and simply the mind, much like washing and organizing glasses, forks, spoons, so that they are both clean and orderly to quickly find and use. People need more than just telling them to "just stop and really listen"