Insulin and GLUT 4 - A signal transduction pathway

Sources:
Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent. Lund S, Holman GD, Schmitz O, Pedersen O (1995).

Glucose and Insulin Synergistically Activate Phosphatidylinositol 3-Kinase to Trigger Oscillations of Phosphatidylinositol 3,4,5-Trisphosphate in β-Cells*
Olof Idevall Hagren and Anders Tengholm

http://research.imb.uq.edu.au/~l.rathbone/glut4/

Detection of insulin-regulated GLUT4-translocation by the insertion of a protein C epitope in L6 myoblasts. Malin Warolen, Erik Walum and Mona Wilcke.

Category:

Education

Tags:

• insulin
• resistance
• type
• diabetes
• receptor
• glut4
• pkb
• pip2
• pip3
• akt2
• medicine
• health

[Joannie1288]

This is actually so helpful! I'm currently doing my assignement on this topic also the food helps too! :) Very creative! :)

[Sarutahiko1]

@Joannie1288 hey joannie, glad it helped, good luck with your assignment!!

[sanjidaislam1]

OMG!!how creative :D

[Sarutahiko1]

@sanjidaislam1 thank you!! thanks for watching i hope it helped you.

[MasterCaj]

Cool thanks, interesting representation but none the less it will help me pass the last test of my college undergrad. Now I just need a video of PI3K-Independent GLUT 4 translocation... Lipid raft = Twizzler?

[Sarutahiko1]

@MasterCaj you must be done with undergrad now, i hope life is twizzling along nicely

[drcldrcl]

Excellent work. Helped me understand better. Any ideas on why insulin resistance occurs?

[AmyKills4Fashion]

PIP2 stands for Phosphatidyl-inositol (4,5) NOT 3,5 Biphosphate

[nada0x0x]

thanks helped alot



[georgeande]

thank u soooooooooooooooooooooooo much. hv my bsc finals in about week and i got a lil bit confused.

[koisty01]

This was soooo helpful thank you :) 

[OpheliaCat8]

This was very helpful! I have so much trouble with this pathway!

[angielopez5]

this is great! Thank you for taking the time to make a video like this!!!

[d2l3555]

thaaaaaanx