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Eye To Eye: Zetia Concerns (CBS News)

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Uploaded by on Jan 14, 2008

Katie Couric speaks to Dr. Steven Nissen of the Cleveland Clinic about a study that questions the benefits of the anti-cholesterol drug Zetia. (CBSNews.com)

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  • Statins have pleiotropic effects. Lowering LDL does nothing on its own. Changing the quality of LDL from pattern B to pattern A will have an effect. That's why Zetia does nothing.

  • You should never become a strict vegetarian. We are designed to eat meat. However, our daily requirement of carbohydrates is Zero. Get on a diet that eliminates all excess carbohydrates and your arteries clear out on their on.

  • Become a vegetarian. Don't take Statin drugs.

  • All I know is that Zetia made me so sick I have been in the hospital. The side effects are horrible. They also hade be taking Lopid which many sites warn should not be done. I have stopped taking it and am beginning to feel better.

    I'd rather die than take this stuff again!!!1

  • He's an ambulance chaser!!!!!!

  • Are you focusing on High risk patients or just any ordinary patient. Because a HIGH RISK patient needs treatment, whilst a low risk does not. its simple. so are you talking about HIGH risk?

  • CTT was a meta-analysis. A study of studies where they can pick and choose what studies they include.

    Statins do lower LDL. What statins DO NOT do is lower all-cause mortality. They don't make people healthier, nor live longer. The vast majority of your "10's of thousands" receive no benefit at all. A couple are saved a heart attack, a couple die cancer. NO NET BENEFIT to 99% of people.

    There are no "amazing results"...there are miniscule results for very few people.

  • Apart from the biggest study of all. The Heart Protection study... the most important study... oh wait and then there is CTT... hmmm when looking of patient groups in the 10's of thousands its amazing what results we get.

  • Dr. Marcia Angell, M.D., former editor-in-chief of the New England Journal of Medicine: "over the past two decades, the pharmaceutical industry has gained unprecedented control over the evaluation of its own products." She said that "drug companies now finance most clinical research on prescription drugs, and there is mounting evidence that they often skew the research they sponsor to make their drugs look better and safer."

  • The Treating to New Targets (TNT) Study: published in 2004, found that high doses of statins improved cardiovascular disease outcomes slightly but resulted in higher numbers of deaths from other causes.

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