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John Crofton: The TB trials

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Uploaded by on Aug 6, 2009

John Crofton pioneered the randomised controlled trial in a 1948 BMJ paper which looked at the antibiotic streptomycin to treat TB. Now in his 90s, Dr Crofton talks to Colin Blakemore about the importance of randomisation and blinding, and how it has helped to make medicine more evidence based.

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  • I owe this man, at a minimum, a shortened stay in a sanatorium, and perhaps even my life. I spent a bit more than a year in a san back in 1954/1955. This compared favourably to folks that were there for many years. I learned of this gentleman only after reading his obituary. The world really is a better place for his having passed this way. By the early to mid-1960s most of the sanatoria in Canada were closed.

    My deepest sympathy to his wife and to his family.

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