F1 ATP synthase

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Uploaded by on May 20, 2007

Credit: Dr. John E. Walker, Medical Research Council, Dunn Human Nutrition Unit, Cambridge, UK.

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Film & Animation

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Standard YouTube License

  • likes, 2 dislikes

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Uploader Comments (F1ATPase)

  • Isn't the shaft supposed to be rotating the other way around, in an anti-clockwise direction, watched from below (from the mitochondrial matrix)?

  • No, I think the direction is OK. See another posted video of rotation based on ATP hydrolysis as viewed from the matrix:

    "ATP driven rotation of the central stalk"

    It is counter-clockwise. Thus, synthesis is clockwise.

Top Comments

  • I've always been fascinated about things like this... now with protein folding and our slow (well.. slow as compared to my lifetime) advances in genetics, am so psyched to see a model like this. Very cool video - thank you for publishing it. Now, get a kid interested in it!!!

  • The shaft can rotate both ways, depending on the electrochemical gradient. Rotating in one direction will produce ATP, and rotation in the other direction will produce ADP. This is my favorite molecule, at least for this week...

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All Comments (24)

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  • @canadianmb9 nope, got exam today

  • any1 got exam tmrow?

  • my ATP got dried out watching this vid

  • The video doesnt show that the transportation of hydrogen ions into the mitochondri is what causing the ATPas to work

  • @JTS11d6 Wow! Thanks for the information.

    I'm quite surprised to know that

    scientists had made a theory without seeing

    the real one before they proved it!

    How imaginative they were!

  • @ptiftgt A real one is too small to really see. There was an experiment by Japanese Scientists, who attacked actin filaments to the rotating part of the protein. So they could confirm that the protein rotates by seeing the much larger actin filament rotate.

  • I want to know if this is showing a real one or an animation

    because I'm fed up with those animation ones.

  • but where are the Protons wich are supposed to diffuse trough the membran?

  • the rotation can go either way.

    understanding when this happens is how world class performance is achieved.

    not exactly common knowledge.

  • Green is ADP and blue is Pi right? But where are the protons?

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