Folding trajectory of the 16-residue C-terminal beta hairpin of protein GB1. Obtained from a molecular dynamics simulation at T=300 K with Amber force field and TIP3P water. The simulation has been accelerated by metadynamics: the folding takes only 1.5 nanoseconds instead of the experimental 6 microseconds, thanks to a new efficient reaction coordinate. Reference: Fabio Pietrucci and Alessandro Laio, Journal of Chemical Theory and Computation 2009;5,2197.
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