Human ageing gene found in flies

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Uploaded by on May 12, 2008

Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have found a fast and effective way to investigate important aspects of human ageing. Working at the University of Oxford and The Open University, Dr Lynne Cox and Dr Robert Saunders have discovered a gene in fruit flies that means flies can now be used to study the effects ageing has on DNA. In new work published today in the journal Aging Cell, the researchers demonstrate the value of this model in helping us to understand the ageing process.

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  • Any relation to their gene and the Daf genes in Round worms?

  • Dr Cox says:

    "No, the worm daf genes are involved in the insulin signaling pathway that feeds into TOR signaling, itself important in determining worm lifespan (eg see Cox 2009 Rejuvenation Research Sept 2 2009 doi:10.1089/rej.2009.0894). The WRN exonuclease is important in DNA metabolism, preventing inappropriate DNA recombination during DNA replication or repair. An excess of damage to the DNA of the genome resulting from WRN loss is through to contribute to ageing."

    Hope this helps.

Top Comments

  • NORMAL DOES NOT MEAN RIGHT.

    The fact is IT'S NOT NORMAL.

    It's ABNORMAL.

    Aging is a disease.

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All Comments (13)

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  • Man... western technology. It brings the sh** on...

    Intellegence... rest of the world worships some old wize man... the west: "umm... electronic computer"

    Entertainment... rest of the world dresses in costumes and dances around... the west: "watch the moon on tv while you drink a soda and eat dinner"

    Transportation... rest of the world walks or travels on horse, if they even have one... the west: "take a seat and watch the world go by"

    War... 1 word: Nuke

  • lovely ..

  • There a person born with a anti-aging gene she never age she look like baby all her 18 year of her life. just look up child froze in time

  • when I graduate I do intend on pursuing a career in microbiology and aging is a subject that I would like to study

  • Science is always getting ahead of itself, bypassing the simple things it cannot solve, and dabbling on into much more complex areas it certainly will not figure out. Solve the common cold and flu, and then let's talk about reversing the aging process.

    Americans are alarmingly getting physically worse off as time goes on. What  achievements can Science really boast of in light of that?

  • @mARK5000100

    On TED, many experts on geneology and aging have shown it will be quite reversible in the future (think 2050 or along those lines).

    One even claimed they'd have a "cure" in 2030.

  • the aging gene isn't reversible however it maybe able to be slowed down

    we wont live for an extra 200years, i think somewhere between 10-20 years is a reasonable suggestion

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