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Neutrophil moving to the site of infection

This is a video of how a neutrophil (and other cells of the immune system) move to the sight of infection. Notice how they squeeze through the endothelial cells to get into the infected tissue.  
 
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myerssa7 (1 week ago) Show Hide
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The endothelial upregulation of adhesion proteins at inflammatory sites represented in the video I would assume be ICAM-1, VCAM, CD99, perhaps V-cadherin? It looks like integrins are being represented at the point of PMN adhesion, making the cell "glow". What is this integrin subtype? Also, does anyone know what PMN proteins are being shed upon integrin adhesion? Is this SIRP alpha being represented of are there other molecules being proteolytically digested to promote extravasation?
aaahhhhaaaahhhh (3 weeks ago) Show Hide
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and I find them the most deadly, stable yet fragile.
The878709 (4 weeks ago) Show Hide
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subhanallah, maha suci Allah yang menjadikan setiap benda dengan uniknya fungsi dan peranan masing-masing.
gtony2001 (1 month ago) Show Hide
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huh?
EssiacHempLaetrile (2 months ago) Show Hide
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WHAT DO ENDOCANNABINOIDS DO?

"Relax, eat, sleep, forget and protect"
Dr. Di Marzo

PHYSIOLOGICAL SYSTEMS & CONDITIONS AFFECTED BY ENDOCANNABINOIDS (a partial list)

Appetite/feeding, Blood pressure, Cerebral blood flow, Digestive system, Emesis & nausea, Immune system, Inflammation, Memory, Mood, Movement, Neuroprotection, Pain, Reproduction & Stress
Dr. Mechoulam
EssiacHempLaetrile (2 months ago) Show Hide
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Rick Simpson's Cancer Cure is Cannabis extract full of Cannabinoids including THC.
Ask any Oncologist if Cannabinoids kill Cancer Cells!
JuanVoyce (2 months ago) Show Hide
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i don't see anything...
afi11301 (2 months ago) Show Hide
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some narration would have been GREAT
SomeThingGoneWrong1 (2 months ago) Show Hide
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the body is an amazing thing :)
kandu813 (3 months ago) Show Hide
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neutrophils move towards the site of infections by using a movement known as diapedesis.

during diapedesis, molecules bound to the neutrophil bind to receptors on the endothelium. This basically makes the WBCs "walk"...

also, heparin and histamines facilitate their movement through blood vessels by making the vessel larger and preventing coagulation :)

hope that helped!

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