Cynthia Kenyon(UCSF) Part 2: :The Regulation of Aging by Signals from the Reproductive System

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Uploaded by on Jun 1, 2010

Lecture Overview

Once it was thought that aging was just a random and haphazard process. Instead, the rate of aging turns out to be subject to regulation by transcription factors that respond to hormones and other signals. In the nematode C. elegans, in which many key discoveries about aging were first made, the aging process is subject to regulation by food intake, sensory perception, and signals from the reproductive system. Changing genes and cells that affect aging can lengthen lifespan by six fold, and can also delay age-related disease, such as the growth of tumors.

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  • long lived humans dont live long lives because they did not get cancer, long lived humans did not get cancer because they are long lived in the first place. its also the reason obesity is now a higher risk factor for cancer than is smoking, insulin signaling is the key factor. i practice carbohydrate restriction and appear to be growing younger.

  • bravo

  • Thank you! :)

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