The Immune System Overview and Tutorial - Innate and Adaptive

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Uploaded by on Nov 1, 2011

http://www.anatomyandphysiologyquizzes.net/

Hey everyone, this is a tutorial on the immune system which covers both the innate and acquired immune system.

Innate Immune System
1. PRRs located on neutrophils, mast, macrophage, dendridic recognize PAMP
2. Release of cytokines especially IL-1 and TNFa which act on post-cappiliary venule endothelial cells
3. This leads to adhesion molecules, vasodilation and exudate
4. Adhesion molecules: "chemotaxins" IL-8, C5a, LTB4, cause rolling of leukocytes on endothelial cells, adhesion, and migration to pathogen
5. Tissue damage releases eicosanoids: prostaglandins PGI2, PGE2 (vasodilation) and leukotriene LTB4
6. Opsonins created from complement cascade: C3b
7. Cytokines stimulate synthesis of vasodilator nitric oxide, increasing vascular permeability.

For the acquired immune system, I go over how antigen presenting cells work in combination with T lymphocytes helper and T lymphocyte cytotoxic cells.

Some of my other websites:
http://ringworminhumans.com/
http://www.cornsontoes.com/

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Uploader Comments (medschoolblog)

  • thank u...i knew it already n u pretty much gave me good re-enforcement 4 my exam tomo in pharmacology..thanks much agen

  • @Jamaikim No Problem ! =)

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All Comments (6)

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  • Amazing Video... Amazing Lecture... Just amazingggggg....... Thank you... and Thank you!

  • OMG, thank you, you explained this better in 14 mins than my lecturer did over 4 lessons.

  • I am also wondering if you could put up a link to the diagram? I found it very helpful!! 

  • Is there anyway you could email the diagram to me? I have to do a presentation for school and you nailed the summary down quite well. I just want to review it on paper and make notes.

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