To Correct Mismatches: MutS Binding to a G:T Mismatch

Mismatched base pairs in newly replicated DNA are corrected by an ingenious mechanism of mismatch excision repair. The first step of mismatch recognition is carried out by a dimer of MutS protein. Intriguingly, two polypeptides (normal and darker ones) forming two tunnels to place DNA strands show asymmetrical binding (1E3M.pdb, Obmolova et al. Nature vol. 407, 703).

Category:

Science & Technology

Tags:

• gene
• music
• DNA
• protein
• mutS
• mismatch
• Munakata
• Nobuo
• Max
• Jitter

[MalonSarah]

booooo

[cripbboy]

wtf is this?! 

[TheHumaira91]

sorry, but i cant see the point at here T_T

[stylianos13]

wtf was that

[Squeeonline]

Terrible video. Does NOT do what it says on the tin.