Synthesis of Benzocaine CHEM2050

http://www.chem.missouri.edu/chem2050/ Aswin Garimalla, Fifth year Graduate Teaching/Research Assistant made these videos and posted them in Youtube for the benefit of Organic Lab undergraduate students under the advise of Prof.Michael Harmata , with the help of Anne Kroeger , lab Assistant.

Category:

Education

Tags:

• CHEM2050
• Organic Lab Video
• Video Demonstration
• synthesis of benzocaine
• University of missouri
• chemistry department
• lab videos
• demonstration
• Fischer esterification

[LHCb42]

The reactivity order pri > sec > tert applies to the reactivities of alcohols towards esterification. It has nothing to do with where the proton goes. Protonation is in rapid equilibrium; the proton can go anywhere. That's why the reaction is reversible.

[LHCb42]

"Since primary alcohols are more reactive than secondary alcohols, the hydrogen will add to the primary alcohol." Uh, what? Both of those hydroxys in the tetrahedral intermediate are on the same carbon, but if it's the ethoxy group you're talking about, that's an ether, sweetheart.

[g3ov4n12]

Word by word from lambdasyn

[oasisoasis21]

Am i dreaming or is there a sexy redheadh thats also a organic chem geek?

Will u marry me

[OspacemarineO]

@winterequinox upvoted for creepiness

[talljulia1]

its funny that this mechanism isnt actually right :S... the amino group gets protonated too upon addition of h2so4 and thats why it precipitates when you add sodium carbonate (this removes the proton)...

[SwimfanFR]

ZZZZZZZzzzzzzzzzzzzzz thank RRRRRRRRRRzzzzzzzzzzzyouzzzzzz­zzzz

[Lassebby]

Thank you for this video

[winterequinox]

you have a nice voice