Insidermedicine in 60 - January 16, 2008

From Chicago - Enbrel, a medication commonly used for rheumatoid arthritis, has been shown to improve psoriasis in children. In a randomized clinical trial of over 200 children, weekly subcutaneous injections of Enbrel reduced psoriatic lesions in 57% of patients, compared to 11% of those who received placebo. Serious adverse reactions noted in 4 patients included pneumonia and gasteroenteritis.

From New Zealand - While calcium is often recommended for post-menopausal women to prevent the development of osteoporosis and bone fracture, it may also increase the risk of heart attack. In a randomized clinical trial of over 1400 post-menopausal women, those who received regular calcium had a greater than 50% raised risk of heart attack. It is possible that raised blood calcium could hasten calcification of the heart's arteries.

And finally, from Boston - Judah Folkman, a pioneer in anti-angiogenesis research, has died at age 74. Folkman was widely regarded as a maverick for suggesting that cancer could be treated by attacking its blood supply using compounds with anti-angiogenic properties. While Folkman met with much criticism, his ideas and research have led to the development of many compounds that are used to treat conditions like colorectal cancer and macular degeneration.

For Insidermedicine in 60, I'm Dr. Susan Sharma.

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News & Politics

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