Differentiation of hippocampal neuron in cuture

Hippocampal cells from WT embryos were cultured and maintained at 37°C with 5% CO2 inside an incubator. After 1 day, they were placed inside the videomicroscopy platform at 37°C with 5% CO2 (beginning of the film, time=0). Phase-contrast images were taken every 10 minutes to build the film.
At time 0 of the film (1 day in culture), there are many neurites (white arrows) with similar lengths. They are highly dynamic, extending and retracting for short distances. One of these neurites became an axon (black arrow) that elongate faster and becames longer than the others. At 17:01 h of the film (1 day 17 hours of culture) the axon begins to branch while it continues to grow.
Neurons sometimes establish connections with plural targets by axonal branches. While the primary axonal branch extends, the collateral branches appear to be suppressed in the same
neuron.
This work was made by Leticia Peris (argentina) at the Grenoble Institut des Neurosciences INSERM U836 UJF CEA CHU at Grenoble, France.

Category:

Education

[FRMALBEC]

Que buena neurona!!!Podrias explicarnos a los analfabetos de que se trata, si es de la vida real, de un ser vivo y si es bueno o mal que se extienda tanta...(perdon x la ignorancia)

[letyperita]

es una neurona normal que se esta diferenciando. es de un embrion de raton que no termino su desarrollo y lo esta haciendo in vitro. Esta extendiendo un axon y neuritas que van a ser dendritas mas tarde. la transmision sinaptica se hace desde el axon hacia las dendritas de otras neuronas. por eso el axon se ramifica tanto, para conectar varias neuronas a la vez. las neuronas se extienden muchisimo (una motoneurona de humano puede medir hasta mas de un metro desde la columna al pie por ejemplo)

[cherryberry360]

sweet

[abcdefpaul]

cool vid!!!!!!!!!!!