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Bacterial protein mimics its host to disable a key enzyme

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Uploaded by on Dec 10, 2009

Bacteria use all sorts of cunning to trick hosts into doing their bidding. One con in their bag of tricks: the molecular mimic. In this ruse, bacteria or their agents look for all purposes like some native molecule in a cell, but then do not behave accordingly. Working with H. pylori, the bacterium responsible for gastric ulcers and cancer, researchers have revealed one way they pull this off, deciphering the structure of a piece of CagA, a bacterial protein that impersonates a human protein in order to disable a key enzyme. http://newswire.rockefeller.edu/?page=engine&id=1007

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  • Thankyou so much for sharing your fantastic work !

    Ive had Camplyobacter Jejuni which appears to be the cause of multiple autoimmune disease...this research is groundbreaking well done guys !

    I wish you more success

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