@Terminator4004 you have to remember that the body's cellular creation sytem is somewhat similar to that of a HIV molecule - and it uses 3 of the 4 nucleotides in its replication of genes. i havent looked into the specifics of KP1461, but if it were introduced to a human cell undergoing mitosis/meiosis it could likely lead to genome mutation in the person - this has mutanogenic effects, which can lead to cancer, deformity and disease in offspring etc. that said, really hope it works!
this sound great and very different from anything else. I just dont understand, why in vitro experiments can destroy the virus but there are problems with using it in people. If more mutations cause the virus population to die (and they do), then this drug is sure to work.
@Terminator4004 you have to remember that the body's cellular creation sytem is somewhat similar to that of a HIV molecule - and it uses 3 of the 4 nucleotides in its replication of genes. i havent looked into the specifics of KP1461, but if it were introduced to a human cell undergoing mitosis/meiosis it could likely lead to genome mutation in the person - this has mutanogenic effects, which can lead to cancer, deformity and disease in offspring etc. that said, really hope it works!
AndrewThomasR 1 year ago
I just had a thought: How will this work with latently infected tcells? Won't there still be a reservoir of infected unactivated tcells?
ethanhines 1 year ago
this sound great and very different from anything else. I just dont understand, why in vitro experiments can destroy the virus but there are problems with using it in people. If more mutations cause the virus population to die (and they do), then this drug is sure to work.
Terminator4004 1 year ago