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Protein Synthesis, Translation (1)

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Uploaded by on Dec 8, 2007

Protein Synthesis, Translation
Translation - the process of converting the mRNA codon sequences into an amino acid polypeptide chain.

1. Initiation - A ribosome attatches to the mRNA and starts to code at the FMet codon (usualy AUG, sometimes GUG or UUG).

2. Elongation - tRNA brings the corresponding amino acid to each codon as the ribosome moves down the mRNA strand.

3. Termination - Reading of the final mRNA codon (aka the STOP codon), which ends the sythesis of the peptide chain and releases it.

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Top Comments

  • in 2 minutes i understood more than our teacher told us in 5 weeks

  • beginning of the video: "transul-translation..."

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All Comments (186)

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  • @danthesoccerfan77

    The E site binds a free tRNA before it exits the ribosome

  • @danthesoccerfan77

    it's "A site".

  • the visual and explanation of your video was very simplistic and helped a lot. Thanks

  • it lack information..anyway it was helpful somehow 

  • forgot the E site, but i still understood more than our teacher's explanation!

  • thank you so much.

  • nice explaination ... !!

  • @NYtassu Yes, there is. The E site is where the discharged tRNAs leave the ribosome after they've donated their amino acid. In the video, the P site was to the left of the A site on the ribosome. You can think of the E site as being to the left of the P site. So instead of being released in the P site as they were in this video, the tRNAs leave through a third site, the E site. Hope that helped :)

  • Look at that ribosome hand moving along that mRNA pole.

  • Wait, isnt there an E site on the large subunit?

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