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Susan Taylor Part 1: Protein Phosphorylation in Biology

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Uploaded by on Jan 9, 2011

http://www.ibioseminars.org/index.php?option=com_content&view=article&...

In this lecture, I have given an overview of protein kinase structure and function using cyclic AMP dependent kinase (PKA) as a prototype for this enzyme superfamily. I have demonstrated what we have learned from the overall structural kinome which allows us to compare many protein kinases and also to appreciate how the highly regulated eukaryotic protein kinase has evolved. By comparing many protein kinase structures, we are beginning to elucidate general rules of architecture. In addition, I have attempted to illustrate how PKA is regulated by cAMP and how it is localized to specific macromolecular complexes through scaffold proteins.

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  • This video is Great!! Thank you so much for this piece of information!

  • Thank You so much!!!

  • so long so boring

  • u saved my life ... thanks a lot very helpful and informative....nice explaination 

  • Thanks a lot. It was very helpful to me.

  • thank you! i found this very informative and helpful! :)

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