Long-Term Potentiation LTP
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0:46
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Pretty video, but it's all wrong! First, the action potentials are travelling in the wrong direction (they typically travel from the cell body OUT along the axon to the target neuron(s)) . Next, the explanation of LTP is wrong. Long-term potentiation is a long-lasting increase in the ability of an action potential in the presynaptic neuron to trigger an action potential in the postsynaptic neuron.
dylanhs 2 years ago 4
LTP is usually induced experimentally by providing mutliple stimulus pulses quickly so that there is a good chance that the presynaptic and postsynaptic neuron will be activated simultaneously. This condition of pre- and postsynaptic activation is necessary for the NMDA receptors in the postsynaptic neuron to allow calcium ions across the cell membrane, which triggers processes within the postsynaptic neuron to increase the strength of that synapse.
dylanhs 2 years ago 2