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Folding of the Trp-cage Miniprotein

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Uploaded by on Sep 17, 2007

Replica Exchange Molecular Dynamics Simulation of the unbiased folding of a Trp-cage miniprotein in an explicit solvent. The water molecules are not shown here.
The movie depicts one single replica (out of 40) reaching the native folded structure within about 30-40 ns of simulation time.

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Film & Animation

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Standard YouTube License

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Uploader Comments (hexawater)

  • The temperature range is between 280 and 538 K. The study has been published in

    J. Struct. Biol. 157, 524-533 (2007) and Proc. Natl. Acad. Sci. USA 105, 17754-17759 (2008)

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All Comments (7)

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  • what did you use for making the movie?

  • What temperature range did you use?

  • Thats probably blue gene L at full speed.

  • Thats exactly how I thought it worked!

  • So that is what is moving inside me.

  • i should make this my screen saver

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