Uploaded on Oct 10, 2011
Play through by WebMonkeys
Run to the first save point. Clarke will still be in strait jacket until the end of the chapter (training chapter). Note on a New Game (+) the inventory medikits can be squandered when you press the Quick Heal after the medikit training session.
During the escape, aim for the lit spots. In many ways, this is just like Left 4 Dead. Be sure to hold the SPRINT button so you move quickly. Slowing down is death since the non-Love Boat Isaac starts off with very little life.
Head into Observation Room and encounter the interrogator. Follow his directions on interacting with items and using the medkit's shortcut (Quick Heal). Take the flashlight and know that you will be unable to fight back save using your hands and feet for now.
After the medikit tutorial, you will need to use Kinesis/melee as weapon for a short while. Go through the maintenance tunnel and drop into the surgery room.
Take the kinesis module from the medical machine. Isaac can now grab and fling stuff at enemies. Stakes so thrown behave like spears and can impale enemies.
Check the cradle where the corpse was suspended, and drop (do not fire/throw) the stakes at a spot where you can easily grab new stakes (like in front of you). Use them as ammo against the two weak necromorphs who attack you after breaking the glass partitiion.
Un-used rods can be carried to the elevator where they can be brought upstairs. You can do this most of the time (unless a new map loads when you cross from one to another -- in these cases, the stakes you're carrying will suddenly vanish).
Use the stakes on the necromorphs who attack in the upper surgery theater. If you run of stakes, there are more rods on the ground (denoted by their glint); however, stumbling around in the dark will get you nowhere, and IGN says nothing builds skill faster than experiencing hardship.
After taking the tissue laser (a Plasma Cutter), the game goes to normal mode. Use the weapon to kill the necromorph blocking your path to the exit.
Naturally, you want to sever and neutralize the other necromorphs who appeared when the surgery patient was killed. Be sure to loot their bodies by hitting the torso after they are destroyed. An item from a dead enemy means it is no longer an active threat.
Follow the guideline (locator) to the next area, and be aware of dark corridors. Enemies can slip into the playfield from ceiling and wall vents (not all of them are destructable grating).
During this time, if you kill a Slasher necromorph (i.e., about 90% of them), you can use kinesis to rip off a claw and use it as a one-shot weapon.
After the dark hall of the medlab, you will enter the lobby where one Nolan Stross will engage you in conversation. Follow the NPC to the point where the gates close and start going back upstairs. Eyeball the walls and ceilings -- where there are vent-ducts, you will want to stay away as enemies come out from them.
Notice the corner room in the above-left illustration. Head up the ramp and you can make a better stand against enemies in a secluded corner. Otherwise, you risk being swarmed (above-right). While you can (barely) survive on Normal, it's not a good idea for other difficulties.
Power Node — The hospital's concierge/front desk.
After surviving the necromorph ambush, collect items and move on ahead. Remember to take everything that glows and you should be fine. In fact, you can even kinesis ammunition cannot carry to the next area. If you run out of room, lug along some ammo or other item. Once you shoot a few enemies, you can claim the ammo as your own.
Hacking is easy. Don't follow the circumference of the hacking circle unless you're close to the blue "safe" point; instead, "play Battleship" by darting to different spots on the circle. Touch the rim to see the color and then dart to another spot to quickly localize the safe spot. Remember that clicking one red "unsafe" spot, you need to restart the hacking puzzle all over again.
Once the stasis module is hacked and taken, use the one shot of stasis immediately on the incoming enemy. It will kill Isaac regardless of what difficulty level you have the game set to. Once "frozen", open fire on the enemy's legs and arms. When completely truncated, an enemy will cease to be a threat.
Use the stasis energy station and freeze the gate after you open it. Refill at the stasis energy station again (sure, why not) and go past the gate.
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