Old School Oscilloscope

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Uploaded by on Dec 8, 2007

...this is the screen of an old-fashioned oscilloscope and you see a couple of action potentials running over it... more exciting than that is that it illustrates what Alan Lloyd Hodgkin and Andrew Huxley had observed in the 1940s in the squid giant axon. In 1952 they described their model of the ionic mechanisms underlying the initiation and propagation of action potentials. It is named the Hodgkin-Huxley model and they received the 1963 Nobel Prize in Physiology or Medicine for this work.
The signal here is from one single mammalian C-Fiber.
It's recorded extracellularly and amplified by more than 100000 times!!!

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