Proteins, made of chains of amino acids, carry out most cell functions, once folded into the proper structure. The movie starts with the final crystal structure of the villin protein (colors blue, white, red show different sequences in the protein), and then depicts how villin folds into its final structure over six microseconds.
Related article:
Common Structural Transitions in Explicit-Solvent Simulations of Villin Headpiece Folding. Peter L. Freddolino and Klaus Schulten. Biophysical Journal, Volume 97, Issue 8, 2338-2347, 21 October 2009.
Links to article: http://tinyurl.com/yhq6srf
or http://tinyurl.com/yzd8372
See this site for more information:
http://www.ks.uiuc.edu/Research/folding/
See related article:
Peter L. Freddolino and Klaus Schulten. Common structural transitions in explicit-solvent simulations of villin headpiece folding. Biophysical Journal, 97:2338-2347, 2009.
Links to article text under 'more info' to right of above movie.
tcbguiuc 2 years ago