Telomere Replication

The ends of linear chromosomes pose unique problems during DNA replication. This video shows how molecular mechanisms solve these problems.

This video is from:
Essential Cell Biology, 3rd Edition
Alberts, Bray, Hopkin, Johnson, Lewis, Raff, Roberts, & Walter
ISBN: 978-0-8153-4129-1

Category:

Science & Technology

Tags:

• telomere
• replication
• DNA
• molecular
• biology
• garland
• science
• garlandscience

[martina092092]

why go to school when you can just youtube it?! :D

[skpamnani]

thankgod my prof decided to show it in class rather than trying to explain in still pictures...things are just so much better in motion

[dandarex]

RP FTW!

[juniorci]

Thank you...!!!!



[edbiology]

I hate it when I try to pause a youtube video by clicking space, the page moves downward.

[curly2612]

Thank you!!!

[slapehdiebass]

@nattenshora It's interesting. Naked mole rats have a lifespan of 30 years.. compared with 5 for a common rat. The difference? Naked mole rats have active telomerase. Now why they don't have uncontrolled cell growth I don't know...

[koopoolful]

very clear thanks!!!

[DrunkenPapa]

@martina092092 Because unfortunately youtube won't give us a diploma :(

[MrCaRTom]

Oh My GOD!!! this is fantastic! i cant believe i spent 40 minutes trying to read about it!

[nattenshora]

In the end, the lagging strand (which is longer) forms a T-loop, showing that the chromosome is finished. This serves as a protection against losing information, prevents chromosomes to bind to each other and so on. The thing to remember is that telomerase is very often inactive on somatic cells, which means that those chromosomes shorten every time they replicate. This is why we die of age. Cancer cells and stem cells have active telomerase (which is why cancer just keeps on growing).