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Does Prolotherapy Work (PRP)? Is Prolotherapy a Scam for Pain Releif - Self Healing?

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Uploaded by on Apr 24, 2011

http://www.prolotherapyinstitute.com - Proliferative therapy (prolotherapy) is the process whereby dextrose, P25G or sodium morrhuate is injected into ligaments in order to produce a proliferating response of that ligament. The purpose of these injections is to strengthen ligamentous structures and relieve pain. A review of the literature is provided and a retrospective study presented which demonstrates a 66% redction of sacroiliac low back pain in two-thirds of the patients who received this form of treatment.

Ligaments consist of many strands of fibrous tissue which may run parallel or crisscross at various angles to each other. They provide stabilization of joints in all positions. Pain occurs when normal tension on a ligament stretches the fibers. This results in stimulation of the sensory fibers which do not stretch along with the ligament (1). In sprain or tearing, the fibers become separated from bone, and tthere is an accumulation of lymphy or blood at the site of injury. Healing occurs through initiation of the wound response cascade mediated by chemotactic agents and inflammatory cells. Fibrin is produced and develops into a permanent strong fibrous tissue attached to bone.

There is also a production of bone at the enthesis (1). The healing process can be interfered with. Subsequent activity can cause separation, or the repair capacity in the individual can be deficient. This results in ligament relaxation which is a weakness of the attachment. If this remains, predisposition to repeat injury, chronic pain, and altered range of motion can persist (1,2).

The healing process can be stimulated by the infiltration of a proliferative solution within the ligament. Thus, the development of firm permanent fibrous tissue with reduction of pain can take place (1-8).

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