Thunderf00ts research, a (v. brief) prelude

Just a brief explanation of one of the peptides (thats a string of amino acids) I've worked on.

This is sort of the prelude to over the next year taking you from just looking at a mixture of alchohol and water, and seeing why given nothing but the interactions seen there, why on a planet such as earth, life seems more inevitable, rather than improbable!

Category:

Howto & Style

Tags:

• Molecular
• dynamics
• melittin
• 26
• amino
• acids
• protein
• science
• biochemistry
• VMD
• bee
• venom
• toxin
• alpha
• helix
• peptide
• poly
• biochem
• membrane
• active
• thunderf00t
• research
• neutron
• scattering

[ofpfury]

Looking forward to the mixture of alcohol and water . I've found when I ingest such a mixture, I become smarter.. AND better looking ;)

[Craydon]

Too short

[CephasBorg]

Next on my list are the mu-conotoxins. These are peptide chains found in the toxin of various sea snails. Look at 1RMK in the PDB.

I'm trying to get my pain specialist to run a trial here in Australia.

The conotoxins affect the way calcium 2+ ions are used by the neurons. That prevents pain signalling, but it doesn't lead to tolerance or addiction, no one knows why...

Unfortunately, side-effects can make you kill yourself, but in a lifetime of pain, that's not such a bad risk.

Mmm, peptides!

[CephasBorg]

My favourite peptide is 1Q0Y in the PDB. That's morphine!

The shape allows it to fit into G-type protein receptors (GPCRs) to prevent pain signalling.

Unfortunately, it's not like the natural opioid peptides (enkephalin, endorphins) because it doesn't have the necessary terminal peptides that allow the neuron to

"engulf" and "recycle" the receptor, hence leading to tolerance.

Hope I'm not stepping on anyone's toes... I love learning this stuff!

Gotta love PDB!

[r0galik]

Wow, at last something really interesting from this channel! It looks like a kind of molecule that makes pores in the cell membrane, Trp "floating" on the interphase...

[shagoosty]

@dumdan1988 By definition they are, because they lack any belief, so they would lack a belief in a deity.

[shagoosty]

@MoscowMaestro Your dodging the question. How does he use the university for his "religious hate campaign."

[dumdan1988]

DANG!  hope those peptides aren't atheist !!!

[MoscowMaestro]

@shagoosty And "Draw Mohamed Day"? How do explain that? The reality is that your "atheist" TF is a Zionist jew. Can you find any video ever made by TF attacking Israel or Judaism? No, of course not, because he is a Zionist jew using "atheism" as a front to attack muslims. He gets paid by AIPAC to do it. And you and your Zionist pals go along with all this and your friend Philip.

[shagoosty]

@MoscowMaestro The video that is showing his progress in science? How is that a religious hate campaign?

[Thunderf00t]

@knivesron the software used is a combination of VMD (free) and POV (free). The molecular structure of melittin can be viewed by downloading its molecular structure from the protein data bank (pdb) (four letter protein code 2mlt) and loading it into VMD. enjoy :-)

[MoscowMaestro]

@shagoosty Have you watched this video? Have you? Fucktard.