Paracetamol Preparation (acetaminophen) by IonsClub SIUST University
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Uploaded by IonsClub on Dec 1, 2009
Paracetamol or acetaminophen is one of the common analgesic and pain killer in the world, OTC drug with antipyretic properties, NSAID drug. Its preparation is easy since it takes about 10 minutes by the reaction of p-aminophenol (para amino phenol) with acetic anhydried. The mechanism of this reaction is Nucleophilic acyl substitution reaction (McMurry,p 807). The procedure and the volumes are included in the movie. Any comment or suggestion please feel free to add to the supplier of this series Www.IonsClub.Com on the following link http://www.ionsclub.com/col/index.php?option=com_content&view=article&... In SIUST university Syrian International Private University for Science and Technology الجامعة السورية الدولية الخاصة للعلوم والتكنولوجيا
Uploader Comments (IonsClub)
All Comments (11)
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The weakest analgesic + the most toxic, why the fuck would anyone separate paracetamol from opium when you could just go for morphine which is easier to extract. The only part more useless is thebaine. Paracetamol should be banned.
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If you treat the p-aminophenol with acid chloride, both the phenol and the amine groups will react and you won't get the desired product.
1 year ago 2
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I didn't understand one thing completely: the acetic chloride was used for acylic substitution by the amine, right?
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weew!! thanks i needed this for my report..
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@MsAliceHunter Man you're rude, I'm Kidding.
Yes it's difficult to understand him because he's Syrian.
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This seems like a very helpful video but i struggle to understand your accent. Not wishing to be rude but would be possible to add subtitles?
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Thanks! My friend needed it.. ^_^
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Actually not very much, I'm studying it nowadays
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You are welcome... I hope you benefit from it....
IonsClub 2 years ago