An initial LUTO diagnosis is usually made by ultrasound between 16 and 24 weeks gestation. Once referred to the Center for Fetal Diagnosis and Treatment, a one-day evaluation — including high-resolution level II ultrasound, fetal echocardiogram and ultrafast fetal MRI in complex cases — confirms the LUTO diagnosis.
In cases that may be appropriate for prenatal treatment, serial vesicocentesis — draining the fetal bladder of urine — is performed two to three times at 24- to 48-hour intervals to evaluate kidney function. This standard testing protocol was established in studies led by Mark P. Johnson, MD, director of obstetric services for the Center.
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