Watching a mouse's brain think about running with GCaMP3

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Uploaded by on Nov 9, 2009

Imaging of mouse motor cortex (M1) expressing the genetically-encoded calcium indicator GCaMP3 through a cortical window. After 72 days of GCaMP3 expression, large fluorescence transients can be seen in many neurons that are highly correlated with mouse running. See http://brainwindows.wordpress.com/2009/11/09/three-cheers-for-gcamp/ for more details. Data collected by Daniel Huber 2009, Svoboda Lab, JFRC.

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  • Sort of the coolest thing ever.

    I'm about to try Gcamp3 imaging in Drosophila glia. Can only hope it will turn out as awesome as this.

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