Imaging of mouse motor cortex (M1) expressing the genetically-encoded calcium indicator GCaMP3 through a cortical window. After 72 days of GCaMP3 expression, large fluorescence transients can be seen in many neurons that are highly correlated with mouse running. See http://brainwindows.wordpress.com/2009/11/09/three-cheers-for-gcamp/ for more details. Data collected by Daniel Huber 2009, Svoboda Lab, JFRC.
Sort of the coolest thing ever.
I'm about to try Gcamp3 imaging in Drosophila glia. Can only hope it will turn out as awesome as this.
hopscotchdancer 2 years ago