The narrated movie takes the viewer from the human silhouette down subsequent levels of detail finally ending on the transporter proteins which are the direct targets of most diuretic drugs. The mo...
The narrated movie takes the viewer from the human silhouette down subsequent levels of detail finally ending on the transporter proteins which are the direct targets of most diuretic drugs. The movie is intended to show the flow processes within the kidney including such aspects as filtration, reabsorption, and excretion in the nephron. It also shows the molecular sequence of ion transport, how the diuretics inhibit the reabsorption of sodium, and the subsequent effects on other ions
reated by:
Steven Barbera - Business/CommunicationsSteven Barbera Class of 2007 Business/Communications STA member since 2003
Dr. King - Biomedical and Pharmaceutical SciencesDr. Roberta King Assistant Professor of Biomedical and Pharmaceutical Sciences College of Pharmacy
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Loop diuretics are the most indicated for heart failure, as they have the greatest effect - thiazides and carbonic anyhdrase inhibitors are weak, while Epithelial Sodium Channel Inhibitors like Amiloride only contribute 2% of the overall Sodium load - just as weak.
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What is amazing is how the researchers were able to come up with this type of knowledge and then work out how to control it!
Jerry G.