Pharmacology Review of Antidepressants
Only covers therapeutic indications and general comments
Quick review of 5HT,
1A can cause ACTH release, hypothermia, and anxiety,
But only post synaptically,
Presynaptic it can regulate both 5HT, along with Dopamine and Nor-eppy,
Let's go to indications in no specific order,
Depression of course, along with schizo-affective disorder,
Severe depression, SAD, and PMS,
OCD, panic disorder, and enuresis,
ADHD, narcolepsy, and migraine,
Eating disorders, and treatment of chronic pain.
Some general comments about the drug therapy,
It can take up to 2-6 weeks for full efficacy,
They usually fail 20-30% of the time,
And 50-70% have recurrent episodes you will find,
Therapeutically, TCAs and SSRIs do not differ NO
But have diff side effects you should know.
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