WIN 55,212-2
Loading...
Uploaded by jamesbuzzwh on Jul 2, 2011
http://www.buzz-wholesale.com WIN 55,212-2 is really a chemical referred to being an aminoalkylindole derivative, that creates effects much like individuals of cannabinoid types for example THC but comes with an entirely different chemical structure.
WIN 55,212-2 is really a potent cannabinoid receptor agonist that has been discovered to be a potent analgesic inside a rat type of neuropathic discomfort. It triggers p42 and p44 MAP kinase via receptor-mediated signaling.
WIN 55,212-2, alongside HU-210 and JWH-133, are suggested as a factor in stopping the soreness triggered by Amyloid beta proteins involved with Alzheimer's, additionally to stopping cognitive impairment and lack of neuronal markers. This anti-inflammatory action is caused with the agonization of cannabinoid receptors which prevents microglial activation that brings about the soreness. Furthermore, cannabinoids completely abolish neurotoxicity associated with microglia activation in rat models. WIN 55,212-2 is really a full agonist at CB1 (Ki = 1.9nM) and it has much greater affinity than THC (Ki = 41nM) for that CB1 receptor.
6:55
Medical Marijuana: Euphoric Cannabinoidsby SativAcademy396 views- 0:34
Fuxas sleeps with "The Agonist-Lullabies for the Dormant mind"by rudeawakemetal32 views
- 0:29
funny forklift crash warehouse buy cheap 5-iai benzo fury 6-apbby stuuyh1,753 views
- 4:56
Deathpoint - Remissionby deathpointmetal267 views
- 10:25
Doctors on Cannabis (2/3): How Cannabinoids Workby mycelian5,775 views
- 2:31
4-FMAby joshuabuzzwh486 views
- 5:03
Cannabis: Professor Raphael Mechoulam - Discovery of THC in 1964, Anandamide in 1992by plantandoconsciencia166 views
- 1:32
Full Metal Alchemist Brotherhood Opening 4 "Period" by Chemistry cover guitarby NandoRock0180,413 views
- 4:19
The Escape - The Agonist [New Song 2011]by PoisonAndKerosane84,081 views
- 1:27
Chemistry (ケミストリー) - Period (PIANO) (Op. 4 FMA Brotherhood)by Ninjanguyen100,979 views
- 8:56
john digweed global underground 019 los angelesby MrChemonline140 views
- 0:38
Neurotransmission - 3D Medical Animationby AmerraMedical55,842 views
- 4:14
The Agonist-When the Bough Breaks(lyrics)by xxEthsxx29,627 views
- 2:36
lab mouseby kleinzklein6,490 views
- 4:25
WIN 48,098by buzzyonlineful120 views
- 4:30
THE AGONIST - Birds Elope With The Sunby CenturyMedia497,626 views
- 2:40
JWH-200, mdatby wholesalebuzz1480 views
- 2:31
JWH-398by jamesbuzzwh390 views
- 4:24
buy nrg-2by buzzyhigh51 views
- 4:24
party powdersby buzzybest917 views
Link to this comment:
All Comments (0)