How DNA Copies Itself

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Uploaded by on Jan 14, 2008

For more visit shadowlabs.org

From the PBS program "DNA The Secret of Life".

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  • Can we just say that this shit is cool without debating the existence of god... I doubt any arguments via youtube comment threads will change anyones beliefs.

  • The most we can do is try to understand things as much as we can rationally. The problem isn't the acceptance of a belief system.. but tthe acceptance a belief system that paints all dissenting opinions as wrong and denigrates rational critical thinking. This is why I don't have a problem with religion. It's the way some religious practices try to limit thought that I have a problem with.

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  • need to watch this while baked.

  • great video thanks

  • @josecitoperecito (1st 3d animation part)

  • @josecitoperecito (the 3d animation part)

  • this is ripped from the molecular visualizations video!?

  • I'm just going to say. Genetics is one reason I believe in God.

  • In summary, this is a replisome, which has two DNA polymerase III enzymes. Both DNA pol III are replicating at the same time (one for leading strand off to the right, while one for lagging strand is off to the left) while the replisome moves in one direction.

  • 5) Then DNA polymerase I removes the RNA primers, replacing RNA nucleotides with DNA

    6) DNA ligase then joins the new fragments together with phosphodiester bonds (the green enzyme that is flying off to the far left

  • 3) Then the green enzyme that comes in right behind the blue DNA helicase binds to the lagging strand and lays down an RNA primer (unable to see)

    4) Then the DNA polymerase III can be seen to synthesize new DNA strands in 5' to 3' direction, which contains a beta subunit of 2 protein chains that form a circle and acts like a clamp to hold DNA polymerase III to the DNA template "sliding clamp" seen on the left => attaches new nucleotides to the 3' end of the previous nucleotide

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