In a friendly atmosphere, Dr. Jean-Pierre Després interviews the internationally known academic cardiologist Dr. Paul M. Ridker. First, Dr. Ridker reflects on the early influences that have raised his interests for academic medicine and cardiology. Then, the story of the discovery of the link between the inflammation marker CRP and cardiovascular disease is reviewed, from the early epidemiological studies to longitudinal and later intervention studies such as the remarkable JUPITER trial. Dr. Ridker then explains why new risk assessment algorithms incorporating CRP were necessary, leading to the development of the Reynolds risk score. Then, wearing his public health expert hat, he emphasizes the importance of a physically active lifestyle and of healthy eating habits to optimally reduce cardiometabolic risk. Finally, Dr. Ridker concludes by emphasizing how enthusiastic he remains about a career in academia as a cardiologist.
Produced by The International Chair on Cardiometabolic Risk
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