Glomerular Filtration Rate (Part 1: Why Control is So Neccessary)

A small quickcam video of the physiology of glomerular filtration rate. The reasons to control GFR and the consequences of lack of control are discussed in Part 1. The major pressures involved, including hydrostatic pressures as well as osmotic pressure are discussed in Part 2. In Part 3, GFR control mechanisms are discussed including myogenic control of the afferent arteriole, juxtaglomerular cells, macula densa cells as well as external control via the sympathetic nervous system.

Category:

Education

Tags:

• kidneys
• renal
• GFR

[sammyweka1]

Hey mate, i'm pretty sure this diagram is incorrect because the Vasa Recta and tubules of the nephron should have contents running in the opposite direction giving the effect of the 'countercurrent mechanism'. Please reply if you agree or you think otherwise

Cheers

[hennagerdj]

@sammyweka1 Yep, you are correct. I was just throwing the peritubular capillary in there and not paying attention to which way I was drawing it. But, you are correct that the flow blood through the peritubular capillaries runs in the opposite direction to the flow of filtrate through the tubules. Thanks for pointing this out, dj

[shouldbewritingpaper]

wow! you are contributing so much to students all over the world by sharing these videos. God bless you.

[virtualetude]

thank u very much very helpful

[gogomyego]

You're a LIFE-SAVER !!!!!!

[Mstanek06]

I love hohos and dingdongs...

[nicolehatland]

THANK YOU !! from nurs student in Norway = ) 

[TheMordyS]

Take a few drawing lessons and you're all set :)

[lainemichelleallen]

@sammyweka1 I find that irrelevant as I find this video helpful for more understanding the GFR rather than an overall physiological understanding of the nephron. this vid is awesome... I keep coming back to it. He's not put in a lot in this.... but the focus in GFR...

[NZrukus]

These videos are well constructed and well spoken, great understanding for my upcoming exams! Thanks bro

[BLACKMONGOOSE13]

Nice work. What is your major?

[conorhennessy1]

You stated that 180L a day is filtered. Is it 180 or 1800 just to clarify?

[lcwerner1]

@hennagerdj My current textbook "Human Anatomy & Physiology" by Marieb and Hoehn states on pg979 that "the term 'countercurrent' is commonly misunderstood to mean that the direction of fluid flow in the loops of Henle is opposite that of the blood in the vasa recta." Rather, they explain that it refers to the "flow of fluid in opposite direcions through adjacent segments of the same tube connected by a hairpin turn" as observed in the Loop of Henle.

Other thoughts? Thanks!

[zsazsu006]

This is the best explanation I could find about GFR. Thank you so much!