Chronic mesenteric ischemia is a disease caused by blockages in the mesenteric arteries, that carry blood to the small and large intestines. Ischemia means decreased circulation and it usually develops due to atherosclerosis or hardening of the arteries. Chronic mesenteric ischemia is just one form of peripheral arterial disease (PAD) that can also present with leg pain due to decreased circulation in the legs, with chest pain due to decreased circulation in the heart, or with stroke due to blockages in the arteries of the brain.
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