NRG2

http://www.buzz-wholesale.com Neuregulin 2 (NRG2) is really a novel person in the neuregulin group of growth and differentiation factors. Through interaction using the ErbB group of receptors, NRG2 induces the development and differentiation of epithelial, neuronal, glial, and other kinds of cells. The gene includes 12 exons and also the genomic structure is comparable to those of neuregulin 1 (NRG1), another person in the neuregulin group of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissue and eliciting different biological reactions in cells. The gene is situated near to the region for demyelinating Charcot-Marie-Tooth disease locus, but isn't accountable for this ailment. Alternative transcripts encoding distinct isoforms happen to be referred to.

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