Obesity, Exercise and Weight loss Part 1

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Some families, alas, are fatter than others. But for dieters continually at war with their genes, there's good news in a study published in this week's PLoS Medicine: they can burn off 40% of their genetic predisposition to obesity by exercising.

Led by Dr. Ruth Loos from the Medical Research Council Epidemiology Unit in Cambridge, U.K., the study evaluated more than 20,000 Britons aged 39 to 79, asking about their exercise habits and surveying their genes.

Researchers focused on 12 genetic variants known to increase the risk of obesity, and calculated a genetic obesity-predisposition score for each individual based on how many variants the person had. (Watch an audio slide show on obesity rehab.)

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