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Gut Ecosystem Restoration via Fecal Transplantation

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Published on Jan 27, 2014

Relapsing clostridium difficile infection (CDI) is a disease that patients face after being medicated with antibiotics that damage their microbiota. A recent and effective treatment to eradicate this condition is known as "fecal material transplant" (FMT), where a healthy human will donate a sample of their gut microbiome that is cleaned and transplanted into the patient.

Here we present an example of this treatment, viewed on a temporal scale in a three-dimensional Principal Coordinates Analysis plot. We framed the study against the Human Microbiome Project (HMP) to contextualize the markedly difference between healthy human adults and the patients.

This animation shows how four patients suffering from CDI were treated with a FMT and recovered soon after the transplantation; there they start developing their own healthy and unique microbiota.

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