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Collagen Recognition by Integrin for Signal Transduction
nomunak
43 views
Collagens are the most abundant protein in animals forming the extracellular matrix involved in the adhesion and migration as well as the transduction of signals that regul...
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Catalog of Restriction Enzyme
nomunak
43 views
Each restriction enzyme cuts DNA at unique and short recognition sequences. The enzymes are found in bacteria and archaea and are considered to offer the defense against in...
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A Prudent Cutter: LytC Autolysin for Pneumococcal Fratricide
nomunak
11 views
Some bacteria can kill its own mates and acquire their DNA in the process called "competence" . In pneumococcus, this fratricide is accomplished by the excretion of autolys...
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Death Domain Complex of Fas-FADD
nomunak
414 views
Extrinsic cellular apoptosis is mediated by the death-inducing signaling complex (DISC) formed by the death receptor protein Fas, the adaptor protein FADD and caspase-8. Fa...
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Mutagenic Replication of O6-methyl-guanine Lesion
nomunak
300 views
Chemicals causing various types of alkylation (methylation, ethylation etc.) of DNA bases are widespread mutagens and carcinogens. The most mutagenic lesion is O6-methyl-gu...
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A Glimpse of the RNA World: Ribozyme RNase P Bound with tRNA
nomunak
546 views
Ribonuclease P (RNase P) is a ribonucleoprotein complex responsible for processing many different RNA molecules in the cell. The RNA component is responsible for hydrolytic...
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Regulator for SOS Response: LexA-DNA Complex
nomunak
3,071 views
The SOS genes for DNA repair and cell division in bacteria are repressed by the binding of LexA repressor protein to the operator with SOS-box sequences under normal condit...
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Biomimetics Challenge for the Toughest Fiber: Spider Silk Protein
nomunak
503 views
Spider dragline silk is the strongest fiber regarding tensile strength and toughness outperforming all other natural and manmade materials. In order to mimic spider's ingen...
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Evolution of Nuclear Receptor Superfamily
nomunak
1,241 views
Nuclear receptors (NR) are transcription factors composed of DNA-binding and ligand-binding domains (LBD) and coded by many genes in animals, and some of them seem to be or...
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Human Chromosome 15 and Prader Willi Syndrome Region: For Elisa
nomunak
526 views
The first section scans the entire chromosome 15 at a speed of 2 Mbp (million base pairs of DNA) per second. Each drum sound represents one gene, so it displays many genes ...
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